Metabolomix+ Review: My Full Test Results & What I Discovered

Why I Took the Metabolomix+ Test

I’ve been eating low-carb since 2022, and at one point, I went all in—strict carnivore—as an experiment. Since that time, reintroducing foods has been a major struggle. Even after over a year of trying, my diet is still limited, and the only thing that’s helped is taking digestive enzymes before meals.

I’ve started to wonder if my very low-carb way of eating has had an impact on my nutritional status or vitamin levels. Some people say that you get all the nutrients you need from meat alone. I wanted to explore this theory for myself. I personally believe that everyone is different and what works for one will not work for all in the same way.

I’m always looking for ways to optimize my health, so I decided to take the Metabolomix+ test by Genova Diagnostics—one of the most comprehensive at-home lab tests available. It gives you detailed insights into nutrient levels, metabolism, gut health, and overall wellness, analyzing everything from micronutrients and amino acids to antioxidants, essential fatty acids, heavy metals, and gut markers.

Unlike standard blood tests, this one goes deeper into how your body is actually using nutrients. This is the most in-depth at-home health test I’ve ever done, and I highly recommend it!

Background on My Health & Diet

As far as my health goes, I’ve been dealing with fatigue that’s worsened over the last few months mostly due to thyroid issues, which I am working on with a doctor, so that should improve soon. Over the last year I also experienced sleep problems, and some blood sugar regulation issues at night. I did manage to fix my 3 AM wake-ups with a couple of key changes, but some of those issues return from time to time.

I think it’s important to share some background information on my way of eating. Many people have suggested I add more foods, but that’s easier said than done. Every time I try, I end up with stomach pain, bloating, and other digestive issues. With that said, I do want more variety, so I’ve been slowly reintroducing foods over time. The only way I’ve been able to to so is by taking digestive enzymes. Even lettuce hurts my stomach.

My Diet Mainly Consists Of

• Meat & Animal Products: Ground beef, ground chuck, chuck roasts (majority of what I eat), eggs, steak, ribs, ground pork, chicken & fish (occasionally), and bacon.
• Vegetables & Fruits: Lettuce (recently added), carrots, cucumbers, small peppers, green beans, celery, and chickpeas (occasionally). I’m working on adding in cabbage, but it’s a tough one. Organic berries, peaches. Onions, and garlic.
• Fats & Condiments: Avocado oil-based mayo, Primal kitchen sauces (buffalo), coconut butter, coconut milk, nuts (occasionally), Kalamata olives.
• Other: Seaweed. Spam (occasionally). Small amounts of rice or rice noodles (rarely). Honey (occasionally). Avocado (rarely, due to histamine issues), organic nuts (sometimes).
• For Sleep: At night, after my main meal, I eat a portion of frozen fruit (like peaches or berries) with coconut butter or coconut milk, which seems to help my sleep significantly.

Experimenting with the Diet

Despite my struggles with reintroducing foods, I’m still experimenting with ways to expand my diet without triggering symptoms. Unfortunately many of the non-meat items do trigger symptoms, unless I take a digestive enzyme. But, I hope that changes over time because I want to try to get nutrients from my diet, rather than supplements. My main goal is to support my energy, digestion, and sleep while continuing to optimize my health.

Adding in Carbs

I am open to adding in more carbs and I do that from time-to-time. I don’t like to do that if it leads to excessive hunger. When I do eat some carbs, I tend to either stay in ketosis or go right back into it very fast. But, I am also careful to limit the amount I have because I’m not used to eating many carbs anymore & my blood sugar will really fluctuate from it.

I go through phases when it comes to my diet and sometimes I eat the same thing daily, for a very long time (ie: ground beef/ground chuck). But, then I get inspired and I make some new recipes. I even have a “bread pudding” of sorts that I really enjoy and it has very little impact on my glucose levels, even though it contains some carbs. I haven’t made it in months though.

Daily Diet

When it comes to my daily diet, lately I tend to eat some ground beef/chuck, lettuce, and I make a bit of a dressing from avocado-oil mayo. That is my main staple, but I always like to change things up whenever possible. For example, today I made a Thai chicken coconut curry and a it was a nice change, though chicken isn’t filling at all unless it has skin on it.

With my diet, I plan to continue experimenting with things. I’ve been taking photos of my food over the last six months or so on the Levels app, to track what’s going on with my health and diet. I’ll share some of the photos here. The first one shows an online order of meat because I buy the bulk of my meat online from a couple farms in my state.

Metabolomix+ Test Results

Disclaimer: How I’m Analyzing My Test Results

I’m currently working with a great integrative health doctor, but I won’t be able to go over my results with her for a couple of months. In the meantime, I wanted to dive into the data myself—and I’ve used Claude AI to help me analyze my Metabolomix+ results. I tried using ChatGPT but I found that it didn’t do a very good job of analyzing the data for me.

The AI analysis I received was surprisingly comprehensive—and likely a lot more in-depth and detailed than what I will get with a doctor’s visit. With that said, AI is not always right, so some of the interpretations could be off.

I’m sharing these results as a personal experiment in understanding my own health data, and will update the post if anything is inaccurate. Please take this as a personal experiment, not medical advice. Note: please click on section title to see the test result and AI analysis for each test category.

Summary Assessment: AI’s Overall Analysis

These test results reveal a complex metabolic situation centered around compromised cellular energy production and the resulting adaptations and compensations. The primary issues include mitochondrial dysfunction, significant B-vitamin deficiencies, oxidative stress burden, and digestive challenges, all of which interact to create the current metabolic state.

The good news is that the patterns shown here are consistent with functional, reversible disruptions rather than permanent structural damage. With appropriate, targeted support addressing the underlying biochemical imbalances, significant improvement should be possible.

The most effective approach would likely involve a carefully sequenced strategy that first stabilizes and protects against further damage, then addresses specific nutrient deficiencies, and finally rebuilds metabolic resilience over time.

Understanding the Interconnections: AI’s Overview

What makes these test results particularly revealing is how clearly they demonstrate the interconnected nature of metabolic systems. The patterns suggest:

1. Energy production deficits likely contribute to digestive enzyme insufficiency (the pancreas requires significant energy to produce enzymes)
2. Digestive challenges may limit nutrient absorption, perpetuating deficiencies that further compromise energy production
3. B-vitamin deficiencies affect both mitochondrial function and the body’s ability to handle oxidative stress
4. The compromised Krebs cycle affects not just energy production but also the body’s ability to process various metabolic intermediates
5. Mild toxic burden may be affecting enzyme function at key metabolic steps, as evidenced by specific pathway inhibition patterns

The relatively strong methylation capacity represents an important strength that provides some resilience and foundation for recovery.

Clinical Implications: AI’s Overview

Based on these results and considering the additional health history that was shared, several clinical implications emerge:

1. Addressing the nutrient deficiencies would likely provide significant benefit, especially the severe B2 deficiency which acts as a rate-limiting factor for numerous metabolic processes
2. Supporting mitochondrial function directly could help break the cycle of energy deficit and oxidative damage
3. Digestive enzyme supplementation appears warranted given the clear functional insufficiency shown
4. A careful, phased approach to restoring metabolic balance would be prudent, starting with foundational support before addressing more complex aspects
5. The complex interaction between thyroid function, energy production, and detoxification pathways suggests that a comprehensive, systems-based approach would be more effective than addressing any single aspect in isolation